Best Endpoint Security for Medical and Dental Practices (November 2026)

Executive summary

A small medical or dental practice should start its endpoint shortlist with products whose vendor will sign a Business Associate Agreement (BAA) for the exact edition being bought, because HIPAA requires one whenever a vendor's service handles patient data on the practice's behalf, and should accept that this rules out some managed services that IT providers commonly resell. Just 4 of 17 products on this site are recorded as offering a BAA, and only 0 of that group bundle round-the-clock managed response (vendor data from 2026-11-01). Huntress and ThreatDown, two managed services that IT providers often resell, state that they do not sign BAAs.

The second test is what the product records. Under HIPAA, an impermissible access to patient data is presumed to be a breach unless the practice can show a low probability that the data was compromised (45 CFR 164.402). One of the four factors in that assessment is whether the information was actually acquired or viewed. A product with endpoint detection and response (EDR) keeps an activity record that can help answer it. A product that only blocks malware does not.

HIPAA does not name a product, but that gives most practices a practical reason to choose a BAA-backed product with EDR, plus a named person or service that reads its alerts.

This is general information, not legal advice.

Which Security Rule duties does an endpoint product touch?

The Security Rule never names a product. It lets a practice choose security measures that take account of its size, complexity and capabilities, its technical infrastructure and the cost of the measure (45 CFR 164.306(b)). Five provisions in 45 CFR 164.308 land directly on the workstations and servers in a practice:

The malware and log-in specifications are addressable. Under 164.306(d)(3), that means the practice implements them if reasonable and appropriate, or documents why not and implements an equivalent. It does not mean optional. No dental office has a credible written reason to leave a front-desk PC without malware protection.

Why does the BAA come before features?

An endpoint agent sees file names, paths and sometimes whole files it quarantines. In a practice, those can be patient documents, imaging exports and scanned referral letters. If your risk analysis concludes the vendor's cloud service receives or maintains ePHI, 164.308(b)(1) requires a BAA before you deploy it.

Vendors answer that question differently, and the products below are the ones where the answer is "no" or where the vendor publishes nothing:

Product	HIPAA BAA	Supports PCI DSS	CMMC-relevant	FedRAMP
Bitdefender GravityZone Business Security	Unknown	Unknown	Unknown	unknown
ESET PROTECT Core	Unknown	Yes	Unknown	none
Microsoft Defender for Business	Unknown	Yes	Unknown	unknown
Bitdefender GravityZone Business Security Premium	Unknown	Unknown	Unknown	unknown
Avast Ultimate Business Security	No	Unknown	Unknown	none
CrowdStrike Falcon Go	Unknown	Yes	Yes	authorized
Webroot Business Endpoint Protection	Unknown	Unknown	Unknown	none
ThreatDown Elite	No	Yes	Unknown	none
ThreatDown Advanced	No	Yes	Unknown	none
Sophos Endpoint	Unknown	Yes	Yes	none
Huntress Managed EDR	No	Unknown	Yes	none
Cynet All-in-One	Unknown	Yes	Yes	none
WatchGuard Endpoint Security 360	Unknown	Yes	Unknown	none

Huntress's position is explicit: it states that its products do not access, use or disclose health information, so it does not provide BAAs. ThreatDown (Malwarebytes) says the same about its own products; the source is on the ThreatDown Elite product page. Avast is recorded as not offering one. The other vendors in the table publish no position either way. Microsoft's agreement applies only to services on its HIPAA in-scope list, which names neither Defender for Business nor Defender for Endpoint. Sophos publishes a HIPAA attestation and Cynet maps its reporting to HIPAA, but neither says it signs a BAA. Bitdefender's HIPAA page sends BAA questions to the account manager, and CrowdStrike, ESET, WatchGuard and Webroot say nothing on the point. Ask before you buy, and get the answer in writing. A vendor's view that it never touches ePHI is an input to your risk analysis, not a substitute for it. If your analysis disagrees, the product is off the list regardless of how good it is.

Some BAAs are narrower than the marketing suggests. Acronis, for example, signs BAAs only for Cyber Protect Advanced (or Cyber Protect Cloud) with Acronis Cloud Storage in a US data centre, through an account manager, and not before purchase. The Acronis Cyber Protect page links the source. Whichever vendor you pick, ask for the agreement itself and check which edition it names.

Every tracked vendor's position, in its own words, is in the HIPAA BAA register.

Which BAA-offering products fit a practice?

This table is limited to products recorded as offering a BAA, because for a covered practice the others need a documented risk-analysis exception before they can be considered. SentinelOne Singularity Control is left out of it: it records a BAA and includes EDR, but it keeps no activity history, which is the point of the EDR column here. The columns are the ones that matter after the BAA: whether the product keeps an activity record (EDR), whether someone watches it around the clock, whether it can undo ransomware encryption, and whether it runs on the Macs many practices use at reception.

Product	EDR	24/7 managed response	Ransomware rollback	macOS
Acronis Cyber Protect	Not offered	Not offered	Included	Included
SentinelOne Singularity Complete	Included	Not offered	Included	Included
Trend Micro Worry-Free Services Advanced	Not offered	Not offered	Included	Included

What does it cost a practice?

Product	Per unit per month	10 seats / yr	25 seats / yr	100 seats / yr
SentinelOne Singularity Control	$6.67 /endpoint/mo	$799.90	$1,999.75	$7,999.00
Acronis Cyber Protect	$7.08 /endpoint/mo	$850.00	$2,125.00	$8,500.00
SentinelOne Singularity Complete	$15.00 /endpoint/mo	$1,799.90	$4,499.75	$17,999.00

Count every device that can open patient data: reception PCs, operatory and exam-room machines, imaging workstations, the practice-management server and any laptop a clinician takes home. Microsoft Defender for Business is not in this table because Microsoft's BAA does not name it. If Microsoft confirms coverage in writing, note that it is licensed per user rather than per device, and one licence covers up to five devices per user (Microsoft FAQ), which suits a clinician with a desktop, a laptop and a tablet. Windows and Linux servers are not covered by the user licence; they need Microsoft's Defender for Business servers add-on.

What should each kind of practice buy?

Solo or two-chair practice with no IT staff. If the practice already runs Microsoft 365, Microsoft Defender for Business ($36.00 per user per year) brings EDR, but Microsoft's public list of HIPAA in-scope services does not name Defender for Business or Defender for Endpoint, so confirm with Microsoft in writing that its BAA covers it. It has no 24/7 managed response, so name the person who reads the weekly report and write that into your risk analysis. If nobody can, pay for managed response rather than buying EDR that no one opens.

Group practice of 10 to 40 staff with an outside IT provider. Ask the provider in writing which endpoint product it deploys and whether that vendor signs a BAA with you or with it. If the answer is Huntress or ThreatDown, ask for a BAA-capable alternative or a written risk-analysis conclusion that the service handles no ePHI. Cynet includes a 24/7 team but publishes no BAA position, and its sales orders cannot be cancelled once signed, so get the BAA text before you sign. None of the 4 products recorded as offering a BAA includes 24/7 managed response. SentinelOne Singularity Complete ($179.99 per endpoint per year) includes EDR with 14 days of activity history and records a BAA, but no 24/7 managed response, so agree who watches the console. Singularity Control ($79.99 per endpoint per year) is cheaper but its EDR is limited: it keeps no data retention, so it adds little to a breach assessment.

Practice with imaging servers, Macs or Linux. Check the Mac column above, and each product page's Linux and server support, against your equipment list before you check the price. Several products cover servers only with a separate licence: Microsoft's servers add-on, or Sophos Workload Protection alongside Sophos Endpoint. If an imaging vendor forbids third-party software on its workstation and you leave that machine unprotected, record the reason and the compensating control, such as network isolation, as 164.306(d)(3) requires.

What endpoint security mistakes do practices make?

• Assuming the IT provider's bundle comes with a BAA. Huntress, a managed EDR built for the IT-provider channel, does not.
• Signing a BAA that covers a different edition. Match the BAA's product name to the invoice line.
• Buying EDR and never opening it. 164.308(a)(1)(ii)(D) asks for regular review of activity records. An unread console is a record that nobody reviewed.
• Leaving the imaging PC off the console because it "belongs to the vendor", with nothing written down.

Frequently asked questions

Methodology and caveats

The quoted HIPAA provisions (45 CFR 164.306, 164.308, 164.402) were compared against the official eCFR text on 9 October 2026. The product set in the capability and cost tables is filtered to products whose BAA field is recorded as available; the regulatory table lists products recorded as not offering a BAA or whose vendor publishes no position. BAA status reflects each vendor's published position on its verification date and can change at renewal.

Nothing here is legal advice. Your risk analysis, and your compliance adviser, decide whether a given vendor needs a BAA.

Sources

1. eCFR. 45 CFR 164.308, Administrative safeguards. Checked 9 October 2026.
2. eCFR. 45 CFR 164.306, Security standards: general rules. Checked 9 October 2026.
3. eCFR. 45 CFR 164.402, Definitions (breach). Checked 9 October 2026.
4. Huntress. Huntress and HIPAA Compliance.
5. Microsoft Learn. Defender for Business FAQ.
6. Endpoint Index product pages, each carrying the vendor's BAA statement and its verification date. Dataset last verified 2026-11-01.